Wild Lettuce Extract (4 oz)

Brand: Herbal Gifts, LLC Sold By: TopSelected
$61.58 In Stock
Ships from United States Arrives in 7-14 business days
Item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
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July2026
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July2026
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Wild Lettuce Extract (4 oz)

Wild Lettuce Extract (4 oz)

$61.58

Product Details

Wild Lettuce

Lactuca spp. (L. canadensis, L. sativa, & L. virosa)

This plant is related to common lettuce; Lactuca sativa, but as it’s common name suggest is a wild species. Wild lettuce is cultivated in Austria, France, Germany and Scotland and can be collected from the wild across the southern United States where it has become naturalized, and from Northern and Eastern Europe. Opium Lettuce, another common names for Wild Lettuce harkens to the milky latex substance that exudes when the plant is broken, which was prepared as a substitute for Opium in the 1900’s by physicians. A preparation from wild lettuce was described in the United States Dispensatory of 1898. Although the prepared latex resin from the plant is purported to have some of the same properties as opium, the effects are much more mild and it is not chemically related to any of the opiate drugs.

other names is Wild Lettuce is  known by…

Acrid Lettuce, Bitter Lettuce, German Lactucarium, Green Endive, Lactuca virosa, Lactucarium, Laitue Amère, Laitue à Opium, Laitue Sauvage, Laitue Scariole, Laitue Serriole, Laitue Vireuse, Lechuga Silvestre, Lettuce Opium, Poison Lettuce, Strong-Scented Lettuce.

What is Wild Lettuce?

Wild lettuce is a plant. The leaves, sap (latex), and seed are used to make medicine.

Wild lettuce is used for whooping cough, asthma, urinary tract problems, cough, trouble sleeping (insomnia), restlessness, excitability in children, painful menstrual periods, excessive sex drive in women (nymphomania), muscular or joint pains, poor circulation, swollen genitals in men (priapism), and as an opium substitute in cough preparations.

The seed oil is used for “hardening of the arteries” (atherosclerosis) and as a substitute for wheat germ oil.

Some people apply wild lettuce latex directly to the skin to kill germs.

Some people inhale wild lettuce for a recreational "high" or hallucinogenic effect.

Insufficient Evidence to Rate Effectiveness for...

Whooping cough.

Asthma.

Urinary tract problems.

Cough.

“Hardening of the arteries” (atherosclerosis).

Trouble sleeping (insomnia).

Restlessness.

Painful menstrual periods.

Sexual disorders.

Muscle and joint pain.

Killing germs, when the latex is applied to the skin.

Other conditions.

More evidence is needed to rate the effectiveness of wild lettuce for these uses.

 

Side Effects & Safety

This can cause sweating, fast heartbeat, pupil dilation, dizziness, ringing in the ears, vision changes, sedation, breathing difficulty, and death. Applying wild lettuce directly to the skin can cause irritation.

Wild lettuce (Lactuca virosa) is native to many areas of the world, including North America, Europe and the Middle East.

This herb thrives in sunny locations, such as along riverbanks and roadsides, and can grow up to six feet (1.8 meters) in height.

Wild lettuce has bright green leaves which sprout from a green stem that is occasionally spotted purple.

When scratched, the plant secretes a milky, white substance known as lactucarium.

When dried, this compound resembles opium, a pain-relieving agent extracted from unripe seedpods of the opium poppy. Opium was commonly used as a pain reliever and sedative from ancient times into the 19th century

Today, there are many different wild lettuce products available, containing extracts of the plant’s seeds, leaves and milky sap.

These tinctures, powders, oils and pills are marketed to treat a range of conditions, including anxiety, breathing issues, poor sleep and joint pain.

What’s more, raw wild lettuce is sometimes consumed by foragers who collect and eat wild plants.

In addition, wild lettuce has psychoactive properties and is sometimes used recreationally by people looking for a natural buzz.

Wild lettuce extract, or lactucarium, has long been used to relieve pain.

Lactucarium contains lactucin and lactucopicrin, bitter substances that act on the central nervous system to produce pain-relieving and sedative effects (4

These compounds are considered sesquiterpene lactones, a group of beneficial substances most concentrated in plants belonging to the Asteraceae family — such as lettuce, calendula and chicory

 

In fact, sesquiterpene lactones make up a large part of the milky substance lactucarium secreted by wild lettuce.

While many natural healthcare companies and homeopathic websites promote wild lettuce as a pain treatment, scientific evidence is lacking.

Few human studies have examined wild lettuce and pain relief.

However, some animal studies suggest that the compounds in wild lettuce extract may have impressive pain-relieving properties.

For example, a study in mice demonstrated that at doses of 7 and 13.5 mg per pound (15 and 30 mg per kg) of body weight, lactucin and lactucopicrin, combined, had comparable pain-relieving effects as 30 mg of ibuprofen

However, animal studies on the pain-relieving properties of wild lettuce are limited.

Shipping Overview: 

Shipping: Standard Domestic Shipping within the United States charges first item USD 5.99 and additional item USD 3.0 each. Standard International Shipping from United Kingdom, Germany, Italian and Japan to the United States charges first item USD 9.99 and additional item USD 4.0 each.

Import Duty: Everymarket collects applicable duties and taxes on goods imported into the U.S. at checkout, it's calculated based on the goods value multiply by the rate. For United Kingdom and China goods is 10%, Germany, Italian and Japan goods is 15%. We are committed to making your U.S. shopping experience simple and transparent. The method of delivery—either Delivered Duty Paid (DDP) or Delivered Duty Unpaid (DDU)—depends on whether duties and taxes are collected at the time of your purchase.

Order Processing: Please allow 1-2 business days for order processing and preparation before shipment. 

Domestic Shipping: Orders within the U.S. are shipped via USPS or FedEx, depending on the origin of the product. Average transit times to the United States is 3 - 7 Business days and average transit times to International is 7 - 14 Business days 

International Shipping: Currently, we only ship within the USA. 

Tracking Information: Every order is trackable. You will receive a tracking number once your order has been shipped. Products may be shipped from various global fulfillment centers.

Shipping Delays: 

Please note that shipping times may vary due to factors beyond our control, such as weather conditions, natural disasters, or peak holiday periods. While we strive to ensure timely delivery, the exact arrival time cannot be guaranteed and is managed by the shipping carrier.

Shipping Options:

  • Standard Delivery: Most orders are shipped within 3-7 business days. Larger items may utilize LTL shipping for safe handling.

  • Handling Time: We handle shipments on business days (Monday - Friday), with a preparation time of 1-2 days.

  • Additional Charges: Some items require additional shipping charges due to their size, weight, or special handling. These charges are specified on the product pages and are not eligible for shipping discounts.

  • Exclusions: Gift cards, packaging, taxes, and prior purchases do not count toward the minimum purchase requirement for free shipping. This offer is valid only for shipments to U.S. addresses, including Puerto Rico.

Delivery Details:

  • Estimates: Standard shipping within the US typically takes 3-7 business days. These are estimates and not guarantees.

  • Shipping Restrictions: We ship to all 50 states, Washington, DC, U.S. territories, and APO/FPO/DPO addresses. Shipping options vary based on the delivery address.

  • Remote Areas: Shipments to remote areas may incur additional charges or require pickup from a nearby shipping partner’s location.

Shipping Confirmation:

You will receive a shipping confirmation email with a tracking number as soon as your order is dispatched. If you do not receive this email immediately, please be assured that your items will arrive within the estimated delivery window provided at checkout.

Order Modifications:

If you need to cancel or modify your order, please contact our customer support immediately.

Issues with Delivery:

If your order shows as delivered but you have not received it, please contact the shipping carrier directly to resolve the issue. For persistent problems, contact our customer service at cs@everymarket.com.

Customer Support:

Our team is available 24/7 to assist you with any questions or concerns regarding your order. We are committed to ensuring a smooth shopping experience.

Return & Refund Policy Overview

Please review our return and refund policies below to ensure a smooth transaction process.

Return Policy

  • Duration: You have 30 days from receiving your item to initiate a return.

  • Condition: Items must be unworn, unwashed, with original tags and packaging intact.

  • Shipping Costs: Please contact us to initiate your return, we'll offer return label for free. Otherwise we are not responsible for the return shipping costs of the items.

  • Packaging: Ensure returned items are well-packaged to avoid damage during transit.

  • Tracking: Use a trackable and insured shipping method as we are not liable for items lost or damaged on return.

  • Initiating a Return: Contact us at cs@everymarket.com to start your return. We will provide a return shipping label and instructions upon approval. Returns without prior approval will not be accepted.

How to Return

  • Method: Returns must be sent back by mail to the address provided in the return instructions.

Return Label

  • Please contact us to get return labels.

Product Conditions for Return

  • Eligible Products: Returns are only accepted for items in new condition.

Nonreturnable Items

Certain items are not eligible for return:

  • Electronic devices after 30 days (e.g., computers, laptops, Kindles)

  • Gift cards, prepaid game cards

  • Perishable goods, live insects, some jewelry, some health and personal care items

  • Customized or personalized products

  • Items with special shipping restrictions

Refund Policy

  • Window: Eligible products may be returned within 30 days of delivery for a refund.

  • Refund Method: Refunds are processed to the original payment method or as store credit for items purchased with gift cards.

  • Processing Time: Refunds are processed within 3-5 business days after we receive the return; please allow additional time for shipping and bank processing.

Claims

Inspect your order upon arrival and report any defects, damages, or incorrect items immediately to allow us to address the issue. For claims, contact our support team with details of the issue.

Exchange Policy

For the quickest service, return your original item and place a new order for the desired product once your return is accepted.

Return Address

EveryMarket Customer Service 2101 E Terra Ln, O'Fallon, MO 63366

Customer Support

Available 24/7 for any questions or assistance needed:

  • Phone: +1 (800) 660-3783

  • Email: cs@everymarket.com

 

Wild Lettuce

Lactuca spp. (L. canadensis, L. sativa, & L. virosa)

This plant is related to common lettuce; Lactuca sativa, but as it’s common name suggest is a wild species. Wild lettuce is cultivated in Austria, France, Germany and Scotland and can be collected from the wild across the southern United States where it has become naturalized, and from Northern and Eastern Europe. Opium Lettuce, another common names for Wild Lettuce harkens to the milky latex substance that exudes when the plant is broken, which was prepared as a substitute for Opium in the 1900’s by physicians. A preparation from wild lettuce was described in the United States Dispensatory of 1898. Although the prepared latex resin from the plant is purported to have some of the same properties as opium, the effects are much more mild and it is not chemically related to any of the opiate drugs.

other names is Wild Lettuce is  known by…

Acrid Lettuce, Bitter Lettuce, German Lactucarium, Green Endive, Lactuca virosa, Lactucarium, Laitue Amère, Laitue à Opium, Laitue Sauvage, Laitue Scariole, Laitue Serriole, Laitue Vireuse, Lechuga Silvestre, Lettuce Opium, Poison Lettuce, Strong-Scented Lettuce.

What is Wild Lettuce?

Wild lettuce is a plant. The leaves, sap (latex), and seed are used to make medicine.

Wild lettuce is used for whooping cough, asthma, urinary tract problems, cough, trouble sleeping (insomnia), restlessness, excitability in children, painful menstrual periods, excessive sex drive in women (nymphomania), muscular or joint pains, poor circulation, swollen genitals in men (priapism), and as an opium substitute in cough preparations.

The seed oil is used for “hardening of the arteries” (atherosclerosis) and as a substitute for wheat germ oil.

Some people apply wild lettuce latex directly to the skin to kill germs.

Some people inhale wild lettuce for a recreational "high" or hallucinogenic effect.

Insufficient Evidence to Rate Effectiveness for...

Whooping cough.

Asthma.

Urinary tract problems.

Cough.

“Hardening of the arteries” (atherosclerosis).

Trouble sleeping (insomnia).

Restlessness.

Painful menstrual periods.

Sexual disorders.

Muscle and joint pain.

Killing germs, when the latex is applied to the skin.

Other conditions.

More evidence is needed to rate the effectiveness of wild lettuce for these uses.

 

Side Effects & Safety

This can cause sweating, fast heartbeat, pupil dilation, dizziness, ringing in the ears, vision changes, sedation, breathing difficulty, and death. Applying wild lettuce directly to the skin can cause irritation.

Wild lettuce (Lactuca virosa) is native to many areas of the world, including North America, Europe and the Middle East.

This herb thrives in sunny locations, such as along riverbanks and roadsides, and can grow up to six feet (1.8 meters) in height.

Wild lettuce has bright green leaves which sprout from a green stem that is occasionally spotted purple.

When scratched, the plant secretes a milky, white substance known as lactucarium.

When dried, this compound resembles opium, a pain-relieving agent extracted from unripe seedpods of the opium poppy. Opium was commonly used as a pain reliever and sedative from ancient times into the 19th century

Today, there are many different wild lettuce products available, containing extracts of the plant’s seeds, leaves and milky sap.

These tinctures, powders, oils and pills are marketed to treat a range of conditions, including anxiety, breathing issues, poor sleep and joint pain.

What’s more, raw wild lettuce is sometimes consumed by foragers who collect and eat wild plants.

In addition, wild lettuce has psychoactive properties and is sometimes used recreationally by people looking for a natural buzz.

Wild lettuce extract, or lactucarium, has long been used to relieve pain.

Lactucarium contains lactucin and lactucopicrin, bitter substances that act on the central nervous system to produce pain-relieving and sedative effects (4

These compounds are considered sesquiterpene lactones, a group of beneficial substances most concentrated in plants belonging to the Asteraceae family — such as lettuce, calendula and chicory

 

In fact, sesquiterpene lactones make up a large part of the milky substance lactucarium secreted by wild lettuce.

While many natural healthcare companies and homeopathic websites promote wild lettuce as a pain treatment, scientific evidence is lacking.

Few human studies have examined wild lettuce and pain relief.

However, some animal studies suggest that the compounds in wild lettuce extract may have impressive pain-relieving properties.

For example, a study in mice demonstrated that at doses of 7 and 13.5 mg per pound (15 and 30 mg per kg) of body weight, lactucin and lactucopicrin, combined, had comparable pain-relieving effects as 30 mg of ibuprofen

However, animal studies on the pain-relieving properties of wild lettuce are limited.

Shipping Overview: 

Shipping: Standard Domestic Shipping within the United States charges first item USD 5.99 and additional item USD 3.0 each. Standard International Shipping from United Kingdom, Germany, Italian and Japan to the United States charges first item USD 9.99 and additional item USD 4.0 each.

Import Duty: Everymarket collects applicable duties and taxes on goods imported into the U.S. at checkout, it's calculated based on the goods value multiply by the rate. For United Kingdom and China goods is 10%, Germany, Italian and Japan goods is 15%. We are committed to making your U.S. shopping experience simple and transparent. The method of delivery—either Delivered Duty Paid (DDP) or Delivered Duty Unpaid (DDU)—depends on whether duties and taxes are collected at the time of your purchase.

Order Processing: Please allow 1-2 business days for order processing and preparation before shipment. 

Domestic Shipping: Orders within the U.S. are shipped via USPS or FedEx, depending on the origin of the product. Average transit times to the United States is 3 - 7 Business days and average transit times to International is 7 - 14 Business days 

International Shipping: Currently, we only ship within the USA. 

Tracking Information: Every order is trackable. You will receive a tracking number once your order has been shipped. Products may be shipped from various global fulfillment centers.

Shipping Delays: 

Please note that shipping times may vary due to factors beyond our control, such as weather conditions, natural disasters, or peak holiday periods. While we strive to ensure timely delivery, the exact arrival time cannot be guaranteed and is managed by the shipping carrier.

Shipping Options:

  • Standard Delivery: Most orders are shipped within 3-7 business days. Larger items may utilize LTL shipping for safe handling.

  • Handling Time: We handle shipments on business days (Monday - Friday), with a preparation time of 1-2 days.

  • Additional Charges: Some items require additional shipping charges due to their size, weight, or special handling. These charges are specified on the product pages and are not eligible for shipping discounts.

  • Exclusions: Gift cards, packaging, taxes, and prior purchases do not count toward the minimum purchase requirement for free shipping. This offer is valid only for shipments to U.S. addresses, including Puerto Rico.

Delivery Details:

  • Estimates: Standard shipping within the US typically takes 3-7 business days. These are estimates and not guarantees.

  • Shipping Restrictions: We ship to all 50 states, Washington, DC, U.S. territories, and APO/FPO/DPO addresses. Shipping options vary based on the delivery address.

  • Remote Areas: Shipments to remote areas may incur additional charges or require pickup from a nearby shipping partner’s location.

Shipping Confirmation:

You will receive a shipping confirmation email with a tracking number as soon as your order is dispatched. If you do not receive this email immediately, please be assured that your items will arrive within the estimated delivery window provided at checkout.

Order Modifications:

If you need to cancel or modify your order, please contact our customer support immediately.

Issues with Delivery:

If your order shows as delivered but you have not received it, please contact the shipping carrier directly to resolve the issue. For persistent problems, contact our customer service at cs@everymarket.com.

Customer Support:

Our team is available 24/7 to assist you with any questions or concerns regarding your order. We are committed to ensuring a smooth shopping experience.

Return & Refund Policy Overview

Please review our return and refund policies below to ensure a smooth transaction process.

Return Policy

  • Duration: You have 30 days from receiving your item to initiate a return.

  • Condition: Items must be unworn, unwashed, with original tags and packaging intact.

  • Shipping Costs: Please contact us to initiate your return, we'll offer return label for free. Otherwise we are not responsible for the return shipping costs of the items.

  • Packaging: Ensure returned items are well-packaged to avoid damage during transit.

  • Tracking: Use a trackable and insured shipping method as we are not liable for items lost or damaged on return.

  • Initiating a Return: Contact us at cs@everymarket.com to start your return. We will provide a return shipping label and instructions upon approval. Returns without prior approval will not be accepted.

How to Return

  • Method: Returns must be sent back by mail to the address provided in the return instructions.

Return Label

  • Please contact us to get return labels.

Product Conditions for Return

  • Eligible Products: Returns are only accepted for items in new condition.

Nonreturnable Items

Certain items are not eligible for return:

  • Electronic devices after 30 days (e.g., computers, laptops, Kindles)

  • Gift cards, prepaid game cards

  • Perishable goods, live insects, some jewelry, some health and personal care items

  • Customized or personalized products

  • Items with special shipping restrictions

Refund Policy

  • Window: Eligible products may be returned within 30 days of delivery for a refund.

  • Refund Method: Refunds are processed to the original payment method or as store credit for items purchased with gift cards.

  • Processing Time: Refunds are processed within 3-5 business days after we receive the return; please allow additional time for shipping and bank processing.

Claims

Inspect your order upon arrival and report any defects, damages, or incorrect items immediately to allow us to address the issue. For claims, contact our support team with details of the issue.

Exchange Policy

For the quickest service, return your original item and place a new order for the desired product once your return is accepted.

Return Address

EveryMarket Customer Service 2101 E Terra Ln, O'Fallon, MO 63366

Customer Support

Available 24/7 for any questions or assistance needed:

  • Phone: +1 (800) 660-3783

  • Email: cs@everymarket.com

 

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